Methane is the second-most important anthropogenic greenhouse gas, and wetlands are a major global source of methane emissions. There are large uncertainties in existing estimates of wetland methane emissions. In this study, we use satellite methane data to estimate global wetland methane emissions for the years 2019 and 2020. Then we compare our results with estimates from an ensemble of sixteen process-based wetland models. Our results suggest higher emissions near the equator and lower emissions in mid- and high-latitude regions compared to the mean of the sixteen wetland models. In addition, we find little seasonal change in tropical wetland methane emissions. Our results using satellite data match many process-based wetland models in most major global wetland regions, but some differences remain. These differences show that there are unresolved gaps in scientific knowledge of wetland methane emissions.