Non-invasive geophysical tools can monitor large volumes of the subsurface with relatively high spatial resolution. Spectral induced polarization is a developing geophysical technique which may be able to indirectly measure changes induced from amendment delivery and reactivity, when they induce reactions that impact mineral surface chemistry and polarization (e.g., precipitation or oxidation-reduction reactions). This work demonstrates the ability to non-intrusively evaluate amendment injection delivery and subsequent reactivity at the laboratory scale for a range of amendments under consideration for remediation at the U.S. Department of Energy’s Hanford Site.