- Investigators Workshop | Focused Ultrasound: A Rapidly Growing, New Approach to Epilepsy Treatment
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105 A, Level 1
Overview
Focused Ultrasound (FUS) is a rapidly expanding, new form of incisionless and radiation-free treatment for a wide variety of neurologic and psychiatric disorders. It can target deep structures in the brain for either an ablative (high intensity) or neuromodulatory (low intensity) effect, making it a particularly appealing form of treatment for many types of epilepsy.
This workshop reviews the different mechanisms of action of FUS, current clinical trials for ablation and neuromodulation in epilepsy, as well as preclinical, promising trials of using FUS to open the blood brain barrier (BBB) for targeted drug delivery. We discuss expectations for potential patient outcomes with HIFUS and LIFUS and if these may become part of our treatment catalog, as well as barriers and challenges in development of noninvasive neuromodulatory devices in the field of epilepsy.
Learning Objectives
Following participation in this activity, participants will be able to:
- Recognize the two main forms of FUS transcranial acoustic delivery: HIFUS for ablation, and LIFUS for neuromodulation, and their mechanisms of action
- Outline the current FUS clinical trials in epilepsy, and how this new, emerging neurotechnology is advancing in the field
- Identify the innovative ways FUS is being used to enhance drug delivery to the central nervous system via LIFUS-facilitated opening of the BBB in preclinical trials in epilepsy
Moderator: Ellen J. Bubrick, MD, FAES
Speakers: Charles Caskey, PhD; Vibhor Krishna, MD; and Raag Airan, MD, PhD
Career Stage
Early Career (typically 0-5 years from completion of training)
Mid-Career (typically 6-15 years from completion of training)
Senior (typically >15 years from completion of training)
Demographic
Clinical, First-time Attendees, Research, Young Professionals
Target Audience
Advanced Practice Providers (APPs), Behavioral Health Providers, Clinicians, Fellows/Trainees, Nurses, Pharmacists, Scientists/Researchers, Technicians
ProgramCareer StageDemographicsTarget AudienceSession Content and CE
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